Host Neil deGrasse Tyson brings together celebrities, scientists and comedians to explore a variety of cosmic topics and collide pop culture with science in a way that late-night television has never seen before. Weekly topics range from popular science fiction, space travel, extraterrestrial life, the Big Bang, to the future of Earth and the environment. Tyson is an astrophysicist with a gifted ability to connect with everyone, inspiring us all to to “keep looking up.”

Meet eccentric homeowners whose seemingly ordinary spaces are full of surprises, from a backyard roller coaster to an indoor aquarium.

Comedian Anthony Jeselnik interviews fellow comedians about their careers, influences and other topical issues.

Wickedly talented baker and artist Christine McConnell fills her home with haunting confections, creepy crafts — and wildly inappropriate creatures.

Bravo network executive Andy Cohen discusses pop culture topics with celebrities and reality show personalities.

Bill Nye explores science and its impact on politics, society and pop culture. Each episode tackles a topic from a scientific point of view, dispelling myths, and refuting anti-scientific claims that may be espoused by politicians, religious leaders or titans of industry.

Each week celebrity guests join Irish comedian Graham Norton to discuss what’s being going on around the world that week. The guests poke fun and share their opinions on the main news stories. Graham is often joined by a band or artist to play the show out.

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AMC’s live after-show that serves as a platform for discussion for AMC’s series, Better Call Saul. Hosted by super-fan Chris Hardwick, the half-hour talk show will feature series cast, producers, celebrity fans and more reacting to and discussing the twists and turns of Better Call Saul and taking questions and comments from viewers.

Kevin Hart takes time out of his busy schedule to introduce the world to some of his favorite up-and-coming comedians, including James Davis, Mario Tory and William “Spank” Horton. Now’s their chance to make it big and break on through to the Next Level.

Real Time with Bill Maher is a talk show that airs weekly on HBO, hosted by comedian and political satirist Bill Maher.

Much like his previous series Politically Incorrect on ABC, Real Time features a panel of guests who discuss current events in politics and the media. Unlike the previous show, however, guests are usually more well-versed in the subject matter: more experts such as journalists, professors and politicians participate in the panel, and there are fewer actors and celebrities included in it. Additionally, many guests appear via satellite. Also, Politically Incorrect was produced four days a week and was pre-recorded, while Real Time only produces one episode a week which is broadcast live.

Real Time is an hour-long program with a studio audience, airing live on Friday nights at 10:00 PM. It originates from Studio 33 at CBS Television City in Los Angeles. Prior to 2009, approximately 12 new weekly episodes aired in the spring, followed by another such set of new episodes in the fall. In 2009, the show began airing as one continuous season. Because of the live, current-events nature of the show, HBO does not re-air old episodes between breaks, though occasionally a repeat will be shown when the program takes a week off during the season.